INSPIRE - INtegrated Short-term PallIative REhabilitation to improve quality of life and equitable care access in incurable cancer

INSPIRE vise à tester l’efficacité clinique et économique d’une intervention de réadaptation palliative précoce afin d'améliorer la qualité de vie des patients atteints de cancer incurable. La priorité est également d'assurer une égalité d'accès à cette réadaptation en soins palliatifs de sorte que tous les patients, indépendamment de leur pays et de leur système de santé, puissent bénéficier de soins adaptés notamment via la diffusion des résultats et dans le but de modifier les pratiques actuelles.

Ce projet est porté par G. Economos et associe 11 organisations partenaires de Belgique, du Danemark, d'Angleterre, de France, d'Italie, de Norvège et d'Écosse.

Key information / Informations

•   Funding programme / Programme de financement: HORIZON EUROPE > CLUSTER HEALTH > DESTINATION DISEASE
•   Coordinator / Coordinateur: G. ECONOMOS
•   Partners’ list / Liste des partenaires :

o   HCL - Hospices Civils de Lyon (France)– Coord
o   Lyon Ingénierie Projets - LIP (France)
o   Fondazione Irccs Istituto Nazionale Dei Tumori (Italie)
o   Azienda Unita Sanitaria Locale Di Reggio – Ausl (Italie)
o   University of Bergen (Norvège)
o   Fonden for Almen Praksis (Danemark)
o   EAPC - European Association For Palliative Care (Belgique)
o   European Cancer Patient Coalition (Belgique)
o   The University of Edinburh (Ecosse)
o   King’s College London (UK)
o   Azienda Unita Sanitaria Locale Di Reggio Emilia (Italie)

•   Budget : 2 442 808,25€
•   Grant / Subvention : 2 442 807,25€
•   Début – Fin : 01/09/2022 – 31/08/2026

Context / Contexte

Each year, more than a million Europeans are affected by disability caused by incurable cancer. The consequences of cancer, including disability and a reduced quality of life, can have a profound impact on overall well-being. Though individuals in Europe facing these issues may benefit from rehabilitation in their care, these needs are mostly unmet by current European health systems.

Objectives / Objectifs

The aim of the INSPIRE project is to test the clinical effectiveness and cost of an integrated early palliative rehabilitation intervention to improve function and quality of life in people with incurable cancer.
This will consist of a multinational randomized controlled trial in five European countries in which 340 participants will be recruited to assess the clinical and cost-effectiveness of palliative rehabilitation on quality of life, disability, symptom burden and goal attainment in people with incurable cancer. The intervention can be adapted and integrated into different health systems using existing staff and services, with little or no additional cost.

Expected impact and results / Impact et résultats attendus

Through the collaboration, rehabilitation will gain greater visibility and establish a foundation for future research aimed at improving care for those suffering from untreatable cancer. The analysis of health services will allow for a deeper understanding of discrepancies and diversities in practice, including the organization of palliative rehabilitation services, to better facilitate their incorporation into health systems. The resulting international consensus will provide a blueprint for developing and agreeing upon a globally applicable framework for palliative rehabilitation for individuals with incurable cancer.

LIP’s contribution / Rôle de LIP

LIP will provide assistance to HCL and ensure efficient project management by supporting the overall project coordination, the administrative and financial management and the contribution to legal / IPR management.